What is Stratified Medicine?
Stratified medicine (also described as personalised, precision, or P4 Predictive, Preventive, Personalized and Participatory medicine) uses technical advances in genetic sequencing techniques, and bespoke diagnostic tests, to prescribe the drug that is most likely to have a positive therapeutic effect, at the optimum dose and in the right combination with other medication, to patients at the start of their treatment. Thus patients have their treatment based on their genetic profile, molecular basis of their disease, risk of disease, or response to a particular drug therapy, rather than the signs or symptoms of their disease.
Traditionally patients have been prescribed their medication based on the signs and symptoms of their disease. If a treatment is not successful patients have to be prescribed an alternative medication.
Academic and clinical research has revealed that most diseases have multiple subtypes that require different treatment approaches. Pharmacogenetic data and bespoke diagnostic tests enable clinicians to identify the subcategory of disease and offer patients the most effective treatments from the outset of their treatment.